Frontispiece: Small-Molecule Carbohydrate-Based Immunostimulants
نویسندگان
چکیده
منابع مشابه
Immunomodulators, immunostimulants, and immunotherapies in small animal veterinary medicine.
Immunomodulators, immunostimulants, and immunotherapies are important tools used by veterinary practitioners and researchers to control and direct the immune system of small animals. This article is an overview and summary of some of the most common immunomodulatory agents used in companion animals emphasizing steroidal and nonsteroidal agents, T-cell inhibitors, cytotoxic drugs, immunostimulat...
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Immunostimulants represent an emerging class of drugs for the treatment of infectious disorders and cancer. CpG oligonucleotides and imiquimod, prototypic drugs in this category, are now known to activate dendritic cells (DCs). Here we report the development of a highly sensitive, unbiased functional screen to detect DC-stimulatory signals. Because interleukin-1beta (IL-1beta) mRNA expression i...
متن کاملPhytol-Derived Novel Isoprenoid Immunostimulants
This review describes the adjuvanticity of novel diterpenoids (synthetic phytol derivatives) compared to some commercially available adjuvants. The efficacy of the phytol-derived immunostimulants was evaluated in terms of their ability to activate innate immunity, amplify various antigen-specific immune responses, and engender immunological memory with no discernible adverse effects in both com...
متن کاملImmunostimulants: Types and Functions
Two main compounds are able to enhance immune responses including adjuvants and immunostimulants. An adjuvant is a substance combined with an antigen for increasing its immune response, but an immunostimulant can induce the immune response without injection with an antigen [1]. There are several types of stimulants with different mechanisms and functions such as bacterial products, complex carb...
متن کامل[Hemocyanins as immunostimulants].
Hemocyanins, the giant oxygen transporter glycoproteins of diverse mollusks, are xenogenic to the mammalian immune system and they display a remarkable immuno-genicity. Therefore they are ideal non-specific immunostimulants to treat some types of cancer. They are used as an alternative therapy for superficial urinary bladder cancer (SBC), that has been traditionally treated with Bacillus Calmet...
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ژورنال
عنوان ژورنال: Chemistry - A European Journal
سال: 2017
ISSN: 0947-6539
DOI: 10.1002/chem.201780861